The normal function of sebaceous glands is to produce and secrete sebum, a group of complex oils including triglycerides and fatty acid breakdown products, wax esters, squalene, cholesterol esters, and cholesterol. Sebum lubricates the skin to protect against friction and makes it more impervious to moisture.
Sebaceous hyperplasia causes small bumps to appear on the skin when sebaceous glands become enlarged. ... Too much sebum can contribute to several problems, including acne, oily skin, or an oily scalp. Sebum can also become trapped inside the gland, causing it to swell and form a bump under the skin.
Sebaceous hyperplasia[PROLIFERATION OF CELLS] causes small bumps to appear on the skin when sebaceous glands become enlarged.
Hyperseborrhoea[HYPERSECRETION OF SEBUM] has been considered as a major aetiopathogenetic factor of acne. However, changes in sebaceous gland activity not only correlate with seborrhoea but also with alterations in sebum fatty acid composition. Current findings indicate that sebum lipid fractions with proinflammatory properties and inflammatory tissue cascades are associated in the process of the development of acne lesions. The oxidant/antioxidant ratio of the skin surface lipids and alterations of lipid composition are the main players in the induction of acne inflammation. Nutrition may influence the development of seborrhoea, the fractions of sebum lipids, and acne. Acne is an inflammatory disease probably triggered, among others, by proinflammatory sebum lipid fractions.
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